Interactive PDFs distributed via Canvas/Harmonize introduce a lot of potential for student error since to complete the task they need to download the pdf, open the PDF in Acrobat, fill out the PDF, save the PDF locally, re-upload the PDF to an assignment; so there are five failure points outside of even completing the assignment. In addition, it's very easy to make an error in the creation of these PDFs.
A more elegant solution is described here:
There's a discussion here about using either Google Apps or Office 365 as an integration. In this scenario, a student could view the fillable document within the Canvas course (no downloading or uploading), fill it out and submit it. Here's a video of the process (taken from the link above):